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As is well known, NRL has been used as a material for the production of gloves for almost a century. Throughout the 1990s there were increasing concerns about transmittable diseases, particularly HIV infection and hepatitis, which resulted in a dramatic increase in the use of NRL gloves. Escalating glove use in the 1990s was associated with the rise in reports of allergic reactions to NRL gloves among healthcare workers [1,6,7,8,9,10]. The increased demand for gloves led to an upsurge in glove production, especially in Malaysia. Between 1987 and 1989 the Malaysian Rubber Development Board received over 400 applications to form glove companies where previously only 25 existed [11]. Early on in the history of NRL allergy, some authors [12,13] suggested that the increased production in response to the sudden upsurge for latex gloves often led to inadequate leaching to reduce protein levels.
Deproteinised latex, being composed of enzyme-treated NRL, has also been used as the source material for nitrile gloves. We are not aware of published reports in which gloves made of deproteinised NRL have been compared with conventional NRL gloves, especially with respect to their allergenic properties, although there are reports that NRL-allergic patients can tolerate condoms made from this material [26].
Recently, liquid latex from a North American and Mexican desert shrub, Parthenium argentatum, commonly known as Guayule, has been introduced as source material for gloves [27]. The obvious advantage of Guayule is that it is not botanically related to H. brasiliensis and, for the time being, no reports about type I allergies to these gloves have been reported.
Deproteinised latex, being composed of enzyme-treated NRL, has also been used as the source material for nitrile gloves. We are not aware of published reports in which gloves made of deproteinised NRL have been compared with conventional NRL gloves, especially with respect to their allergenic properties, although there are reports that NRL-allergic patients can tolerate condoms made from this material [26].
Recently, liquid latex from a North American and Mexican desert shrub, Parthenium argentatum, commonly known as Guayule, has been introduced as source material for gloves [27]. The obvious advantage of Guayule is that it is not botanically related to H. brasiliensis and, for the time being, no reports about type I allergies to these gloves have been reported.